Cogitum in the treatment of children with attention deficit hyperactivity disorder and subclinical epileptiform activity on the electroencephalogram

This article outlines the current concept of attention deficit hyperactivity disorder (ADHD) pathogenesis from standpoint neuroanatomy and impairments neurotransmitter metabolism. N-acetyl-aspartate N-acetyl-aspartyl-glutamate are crucial for ADHD development. These substances involved in interaction neuronal networks, myelin maturation, functioning excitatory neurotransmitters (glutamatergic system). The active substance Cogitum is a synthetic analogue N-acetyl-aspartate. We analyzed efficacy 249 children with or without subclinical epileptiform activity on electroencephalogram (children cerebral palsy epileptic seizures were excluded). was most effective improving attention, memory, speech. None had aggravation developed during treatment. Therefore, safe drug to alleviate manifestations electroencephalogram.